Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development
نویسندگان
چکیده
منابع مشابه
Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development.
Sonic hedgehog (Shh) signaling plays diverse roles during animal development and adult tissue homeostasis through differential regulation of Gli family transcription factors. Dysregulated Shh signaling activities have been linked to birth defects and tumorigenesis. Here we report that Brg, an ATP-dependent chromatin remodeling factor, has dual functions in regulating Shh target gene expression....
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2011
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1018510108